Gene-Foci® MaestroScript II Reverse Transcriptase is a modified version of M-MuLV Reverse Transcriptase that has reduced RNase H activity and enhanced RNA-directed DNA polymerase activity. The enzyme catalyzes the synthesis of complementary DNA strand using DNA, RNA or RNA:DNA hybrids as a template. MaestroScript II possesses a much lower RNase H activity than conventional M-MLV RT, providing increased specificity and higher yield of cDNA. It can synthesis cDNA from 0.1kb to 12 kb. MaestroScript II is a useful tool for first strand cDNA synthesis.